The Henry D. Clayton House in Eufaula, Barbour County, is the home of Confederate general and politician Henry Delamar Clayton Sr. (1827-1889) and the birthplace of U.S. congressman Henry Delamar Clayton Jr. (1857-1929), most notable for his authorship of the Clayton Antitrust Act of 1914. The house was built around 1850 and listed on the National Register of Historic Landmarks in 1976.